Prescription medication that controls pain and inflammation associated with osteoarthritis in dogs. Key Benefits Treats canine OA pain and inflammation Easy to adminster with chicken-flavored tablet form that can be taken with or without food. Galliprant is a first-in-class piprant; a non-COX-inhibiting prostaglandin receptor antagonist (PRA) Galliprant does not inhibit the production of many housekeeping prostanoids that maintain homeostatic functions It specifically blocks the EP4 receptor, the primary mediator of canine OA pain and inflammation How It Works Galliprant deploys a new, targeted approach to relieving canine osteoarthritis (OA) pain and inflammation. It does this by specifically targeting the EP4 receptor, helping to keep the GI, kidney and liver homeostatic functions maintained.