Denamarin contains: A stabilised form of the S,S-SAMe isomer, the predominant form synthesised in cells and the isomer which is biologically active Silybin complexed with phosphatidylcholine, which has been shown to be more bioavailable than silymarin alone. The enteric coating of Denamarin protects the SAMe from degradation. Denamarin is also blister packed to prevent oxidation of the SAMe to the non-biologically active R,S-SAMe isomer.