Indications and species of destination * Dogs: Treatment of canine leishmaniasis. Contraindications * Animals with heart failure and / or liver . Side Effects * The toxicity of this compound can sometimes cause toxic manifestations characterized by vomiting , prostration, myalgia and antralgias .   Route of administration * Subcutaneous. Posology * Dogs is recommended to start with 1/2 dose , especially when there is reduced renal permeability progressively increasing to the recommended dose. *  In case of intolerance , you can stop treatment and start again with lower doses. Therapeutic scheme : * The recommended dose is 100 mg of N- methylglucamine antimoniate per kilogram of body weight per day (equivalent to 0.33 ml of solution per kg per day) .  * If it is possible to administer multiple daily injections , the daily dose may be administered as two daily injections of 75 mg of N - Metiglucamina antimonate / kg / 12 h . *  The initial duration of treatment is 3 weeks.  * This may last 1 more week if insufficient clinical improvement is observed.  * To remove parasites,repeated treatments may be necessary .   Special precautions • Manage under strict veterinary control. • Treatment should be accompanied by a serological and etiological monitoring that point the prognosis of the disease and consequently the fate of the animal. • If diagnosed renal failure, associated symptoms should be stabilized or cured before administration Glucantime treatment . • Monitoring of renal function before and during treatment and monitoring of cardiac and hepatic function during treatment is required .